Cinnamomum zeylanicum (Ceylon cinnamon) as a potential pharmaceutical agent for type-2 diabetes mellitus: study protocol for a randomized controlled trial
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Cinnamomum zeylanicum (Ceylon cinnamon) as a potential pharmaceutical agent for type-2 diabetes mellitus: study protocol for a randomized controlled trial
BACKGROUND Previous studies have explored the anti-diabetic effects of Cinnamomum cassia extract in vivo and in vitro. However, there are no studies at present exploring the effects of the indigenous species of Sri Lankan cinnamon (Cinnamomum zeylanicum) in patients with diabetes mellitus. The present study aims to evaluate the potential effects of Cinnamomum zeylanicum extract as a pharmaceuti...
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Purpose: To investigate the anti-diabetic, hepatoprotective and lipid homeostatic activity of Cinnamomum zeylanicum aqueous bark extract on streptozotocin (STZ)-induced type-I diabetic rats. Methods: The animals were divided into three groups (n = 6). of normal rats; streptozotocin-induced diabetic rats; and diabetic rats treated with 200 mg/kg of the aqueous bark extract, respectively. Treatme...
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متن کاملEvaluation of pharmacodynamic properties and safety of Cinnamomum zeylanicum (Ceylon cinnamon) in healthy adults: a phase I clinical trial
BACKGROUND Cinnamon is considered as a treatment for many ailments in native medicine. Evidence suggests that Cinnamomum zeylanicum (CZ) has anti-microbial, anti-parasitic, anti-oxidant, blood glucose lowering properties and beneficial cardiovascular effects. The present study aims to evaluate Pharmacodynamic properties and safety of CZ in healthy adults using a Phase I Clinical Trial. METHOD...
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ژورنال
عنوان ژورنال: Trials
سال: 2017
ISSN: 1745-6215
DOI: 10.1186/s13063-017-2192-0